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ISCB 2014 Vienna, Austria • Abstracts - Oral Presentations 85Wednesday, 27th August 2014 • 16:00-17:30 Monday25thAugustTuesday26thAugustThursday28thAugustAuthorIndexPostersWednesday27thAugustSunday24thAugust revised our approach in an unrealisitc direction. Schlomer and Brannath (2013) proposed group sequential designs based on the fraction approach although they acknowledge some debate in the literature. In this presentation, we shall discuss statistically sound procedures by clar- ifying the definition of assay sensitivity in three-arm non-inferiority trials.

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